In the literature, numerous studies on chemical and pharmacological properties have been reported for its EO and extracts, which include cytotoxic (Xu et al., 2006), analgesic (Aziba et al., 2001), antibacterial (Khan and Omoloso, 2002), and anti-inflammatory potential (Arrigoni-Blank et al., 2004). Traditionally, Peperomia pellucida has been utilized in the folk medicine of several pantropical countries to treat a wide spectrum of ailments and diseases such as skin sores (Arrigoni-Blank et al., 2002), gastrointestinal disorders (Mollik et al., 2010), dysentery, diarrhea, indigestion (Mollik et al., 2010), abscesses and injuries (Bojo et al., 1994). is possibly used because of its taxonomic information published in the book “Nova Genera et Species Plantarum” which was written by Humboldt et al. pellucida (L.) Kunth should be applied since Kunth was responsible for the present classification of this species (previously named by Linnaeus – 1753 – as Piper pellucidum L.) in the genus Peperomia (Mathieu and Posada, 2006). Its scientific name is usually written in books and publications in South America as P. The plant is a weed with heart-shaped leaves and tiny seeds attaching to the cord-like spikes (Mosango, 2008, Ooi et al., 2012). It is an annual, fasciculate short-rooted herb usually having a height of 15–45 cm (Majumder and Kumar, 2011). Stems are succulent, translucent green, erect or ascending, and internodes are usually 3–8 cm long, glabrous and hairless (Majumder, 2011). The species grows well in humid and loose soils in places with reduced solar radiation with preference to rainy periods (Arrigoni-Blank et al., 2004). This plant is an herbaceous herb with succulent, alternate oval leaves and inflorescences in terminal spikes, axillary and opposite to the leaves. 1) is known for its variety of pharmacological properties. Its species are dispersed pantropically, having the greatest biodiversity in the Neotropics followed by Southern Asia (about 100 species), Madagascar (about 40 species), Africa (about 20 species), Australia and New Zealand (less than 20 species) (Wanke et al., 2006). Several Peperomia species are cultivated as ornamentals because of the beauty of their foliage (Guimarães and Carvalho-Silva, 2012). The group Peperomia is one of the largest genera of basal angiosperms (Wanke et al., 2006) and is composed of herbs usually perennial (Shu, 1999). It is among the oldest of the pan-tropical plants and its species are mainly distributed in two genera: Piper with around 2000 species (Quijano-Abril et al., 2006) and Peperomia with approximately 1600 (Frenzke et al., 2015). The Piperaceae is a large family of angiosperms composed of around 3700 species (Christenhusz and Byng, 2016).
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